An Aerial View of Colon, Panama

Colon

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Panama’s Tropical Oasis Awaits!

Fancy waking up to ocean waves and the promise of proper adventure? Our cruises to Colon, Panama are calling your name! We're talking sunrise over lush tropical jungle, the legendary Panama Canal on your doorstep, and enough excitement to keep even the most restless traveler happy. Colon's got it all—fascinating history (yes, actual pirates used to hang out here), gorgeous beaches for those "do absolutely nothing" days, and food so good you'll be Googling flights back before you've even left. The local cuisine? Let's just say your taste buds are in for a treat.

A View of a Ruined Fort and an Old Cannon in Colon, Panama

Here's the thing—at Cruise Nation, we actually care about giving you brilliant holidays without the eye-watering price tag. Romantic getaway? Sorted. Family trip where everyone's actually happy? We've got you. We tailor everything so you get the holiday you want, not some cookie-cutter package tour. So what are you waiting for? Stop scrolling through Instagram dreaming about other people's holidays and book your own cruise to Colon with us. Your adventure at sea is out there ready and waiting—you just need to say yes!

A View of a River in Colon, Panama

Amazing Holiday Deals

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

Average Customer Rating:
4.9/5|
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Independent Service Rating based on 11,625 verified reviews.Read all reviews

Award

Fantastic service and not pushy thank you. And wished Wrexham good luck.

Great service from Scott Very patient with me and lots of advice on trains and buses. We have never been to Canada before and he was very helpful telling us something about Canada. We are really looking forward to our cruise and stay holiday. Thank...

Mrs Karen Bishop-16 February 2026

Cruise and stay holiday

Telephone answered very quickly, very helpful , booked cruise and stay , all questioned dealt with would recommend

Mrs Judith Tebbutt-14 February 2026

Very efficient, helpful and slick.

Mrs Joanne Heather-16 February 2026

Excellservice from Scott in booking our Bucket list trip to the PanamaCanal

Excellent conversation with Scott to book our Bucket list trip to the Panama canal. He was really helpful booking our cabin and getting the exact flights and upgrades. Really appreciated his help so a big thank you!

-15 February 2026