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East Mediterranean Cruises

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"From the azure waters of the Aegean Sea to the sun-dappled shores of Cyprus, every destination tells a story of cultures intertwined through centuries"

Culture, Sun, Serenity

Are you ready to set sail on an unforgettable voyage to the breathtaking East Mediterranean? Imagine gliding through crystal-clear waters while surrounded by storied landscapes, ancient ruins, and the tantalizing taste of Mediterranean cuisine! With Cruise Nation, your dream holiday is just a wave away!

Dubrovnik - Croatia
An Image of the Walls of Dubrovnik in Croatia

From the sun-kissed shores of Greece to the vibrant markets of Turkey, the East Mediterranean is where history and modern life collide in dazzling harmony. Picture yourself wandering through the iconic streets of Santorini, where blue domes kiss the azure sky, or diving into the rich cultures of Istanbul, where every alleyway beckons you with the aroma of spices and freshly baked goods. Trust us, your taste buds are in for a treat!

Santorini - Greece
A view of the blue topped buildings of Santorini

Star Buy

The Iconic white buildings of Santorini

Our exceptional cruise packages provide you with the best value for a truly class-leading holiday experience. Explore the captivating ruins of Pompeii, bask in the beauty of the Amalfi Coast, or journey through the shimmering waters of the Aegean Sea—all while enjoying luxurious amenities on your cruise ship. Why settle for less when you can indulge in world-class dining and enthralling entertainment aboard?

A landscape view of Rhodes
Venice Square

What's the weather like in the Eastern Mediterranean?

There are plenty of great times to cruise the Eastern Mediterranean. But when it comes to weather, certain months are better than others, so before you book it’s good to know the prime times to cruise the region.

Do it your way

Having the freedom to cruise your way is just one of the many reasons why Cruise Nation is the way to go for the ultimate Eastern Mediterranean cruise getaway. We like to keep your options open here. If flying isn’t your thing, then our no-fly cruises do away with baggage restrictions and long queues.

Bari - Italy
The Cliffs of Bari, Italy

Our fly cruises, meanwhile, let you lengthen your leisure time either side of your holiday. Want to soak up the Athenian sun for a few days before you set sail? You can do that. Or maybe you’re not quite ready to leave Rhodes just yet? Simply add a few extra days onto your itinerary.

Istanbul - Turkey
A Landscape shot of Istanbul

Eastern Mediterranean Highlights

A view of the Acropolis of Athens, Greece

Athens

Athens

One of the world’s oldest cities, Athens’ listed historic sites, mythical gods and laid-back lifestyle have kept travellers returning to the Greek capital for hundreds of years. It’s a kind of appeal that won’t be changing anytime soon.

Today, the sprawling city is a perfect blend of old and new: ruins sit next to chic new restaurants, centuries-old artefacts hang side-by-side with modern masterpieces and boutique hotels provide a fresh take on city-dwelling.

No Athens stop on a Mediterranean cruise would be complete without a visit to the Acropolis and the Parthenon, while those looking to indulge in some retail therapy should make for the Plaka – the city’s oldest neighbourhood, lined with pretty boutiques and jewellery stores – for a wardrobe refresh with a twist.

A view of the Acropolis of Athens, Greece

Athens

One of the world’s oldest cities, Athens’ listed historic sites, mythical gods and laid-back lifestyle have kept travellers returning to the Greek capital for hundreds of years. It’s a kind of appeal that won’t be changing anytime soon.

Today, the sprawling city is a perfect blend of old and new: ruins sit next to chic new restaurants, centuries-old artefacts hang side-by-side with modern masterpieces and boutique hotels provide a fresh take on city-dwelling.

No Athens stop on a Mediterranean cruise would be complete without a visit to the Acropolis and the Parthenon, while those looking to indulge in some retail therapy should make for the Plaka – the city’s oldest neighbourhood, lined with pretty boutiques and jewellery stores – for a wardrobe refresh with a twist.

An image of a Grand Canal in Venice, Italy

Venice

Venice

Romance, mystery, and intrigue combine in one of the world’s most-visited cities. The floating maze of streets and winding canals that cover Venice’s 100 islands are easy to lose yourself among, but a short gondola ride will soon see you back at Venezia’s main attractions.

Unmissable sights include the hidden rooms and passages of the Dodge’s Palace in St. Mark’s Square, the beautiful Bridge of Sighs, and the incredible artwork of the Basilica. Bucket lists at the ready…

Venice is also one of the finest cities in the world for food and drink. Avoid the tourist-traps and sky-high prices around the most famous sights and instead dive down a side street, where bars and restaurants are filled with local alfresco diners, sipping elegantly on Aperol Spritzes canal-side.

An image of a Grand Canal in Venice, Italy

Venice

Romance, mystery, and intrigue combine in one of the world’s most-visited cities. The floating maze of streets and winding canals that cover Venice’s 100 islands are easy to lose yourself among, but a short gondola ride will soon see you back at Venezia’s main attractions.

Unmissable sights include the hidden rooms and passages of the Dodge’s Palace in St. Mark’s Square, the beautiful Bridge of Sighs, and the incredible artwork of the Basilica. Bucket lists at the ready…

Venice is also one of the finest cities in the world for food and drink. Avoid the tourist-traps and sky-high prices around the most famous sights and instead dive down a side street, where bars and restaurants are filled with local alfresco diners, sipping elegantly on Aperol Spritzes canal-side.

The skyline of Istanbul

Istanbul

Istanbul

Once the capital of the Eastern Christian Empire, Istanbul has been home to several fascinating cultures – including the Romans, Greeks, and Ottomans. This diverse heritage has had a huge impact on the city, and Istanbul continues to be a cultural capital for art, religion, and traditional Islamic architecture.

With more galleries, museums, and minarets than you can point a camera at, Istanbul’s picturesque array of art and architecture makes for plenty of photo-ready opportunities for the snap-happy. Once you’re finished creating your very own postcard shots, be sure to sample its food, from huge mezes to incredible kebabs, made in ways you won’t have tried before.

And what makes Istanbul even better? It’s the ideal starting point to begin your cruise to the Eastern Mediterranean – within close traveling distance to a number of beautiful destinations including Ephesus and Halicarnassus.

The skyline of Istanbul

Istanbul

Once the capital of the Eastern Christian Empire, Istanbul has been home to several fascinating cultures – including the Romans, Greeks, and Ottomans. This diverse heritage has had a huge impact on the city, and Istanbul continues to be a cultural capital for art, religion, and traditional Islamic architecture.

With more galleries, museums, and minarets than you can point a camera at, Istanbul’s picturesque array of art and architecture makes for plenty of photo-ready opportunities for the snap-happy. Once you’re finished creating your very own postcard shots, be sure to sample its food, from huge mezes to incredible kebabs, made in ways you won’t have tried before.

And what makes Istanbul even better? It’s the ideal starting point to begin your cruise to the Eastern Mediterranean – within close traveling distance to a number of beautiful destinations including Ephesus and Halicarnassus.

An Image showing Rhodes Island

Rhodes

Rhodes

Whether it’s a deep dive into its past or a lounge on the beach, Rhodes offers the best of both worlds. Begin at Rhodes Old Town, where you’ll uncover a twisting labyrinth of cobbled alleys, awe-inspiring architecture, and ruins from Classical, Ottoman, and Italian eras waiting to be discovered.

The New Town, meanwhile, is anything but ancient. A sprawling modern resort, tourists are well catered for here. Festooned with beaches, high-end shops, a bustling nightlife, and plenty of bars to pull up a chair at, it’s a completely different world from the Old Town.

But Rhodes’ true highlight is perhaps its cuisine. Foodies are in for a real treat here; the local cuisine is about so much more than powering you through the day. It’s a way of life. Expect succulent lamb dishes, fresh Greek yoghurt flavoured with herb-infused honey, succulent souvlaki, and locally caught fish that came ashore just hours earlier.

An Image showing Rhodes Island

Rhodes

Whether it’s a deep dive into its past or a lounge on the beach, Rhodes offers the best of both worlds. Begin at Rhodes Old Town, where you’ll uncover a twisting labyrinth of cobbled alleys, awe-inspiring architecture, and ruins from Classical, Ottoman, and Italian eras waiting to be discovered.

The New Town, meanwhile, is anything but ancient. A sprawling modern resort, tourists are well catered for here. Festooned with beaches, high-end shops, a bustling nightlife, and plenty of bars to pull up a chair at, it’s a completely different world from the Old Town.

But Rhodes’ true highlight is perhaps its cuisine. Foodies are in for a real treat here; the local cuisine is about so much more than powering you through the day. It’s a way of life. Expect succulent lamb dishes, fresh Greek yoghurt flavoured with herb-infused honey, succulent souvlaki, and locally caught fish that came ashore just hours earlier.

An image of the seaside town of Bari, Italy

Bari

Bari

Bari might not have the big-name reputation of other Eastern Mediterranean ports, but its hidden-gem status surely won’t last much longer. Once a gritty urban sprawl, Bari’s easy access has given it a new-found energy, a place that welcomes all who step foot on its shores.

Lined with ancient narrow streets, Bari’s Old Town is home to spectacular architecture that dates back a thousand years. Here, you’ll find the relics of St. Nicholas himself inside Basilica di San Nicola, while Bari Cathedral promises unforgettable sightseeing within a peerless Christian Basilica.

Elsewhere, the city has undergone significant renewal, with an array of highlights and tourist attractions introduced in recent years. These more recent sights sit alongside Bari’s bohemian enclaves, with a plethora of exhibitions, film screenings and art workshops bringing a unique cultural flair to this underrated Italian port city.

An image of the seaside town of Bari, Italy

Bari

Bari might not have the big-name reputation of other Eastern Mediterranean ports, but its hidden-gem status surely won’t last much longer. Once a gritty urban sprawl, Bari’s easy access has given it a new-found energy, a place that welcomes all who step foot on its shores.

Lined with ancient narrow streets, Bari’s Old Town is home to spectacular architecture that dates back a thousand years. Here, you’ll find the relics of St. Nicholas himself inside Basilica di San Nicola, while Bari Cathedral promises unforgettable sightseeing within a peerless Christian Basilica.

Elsewhere, the city has undergone significant renewal, with an array of highlights and tourist attractions introduced in recent years. These more recent sights sit alongside Bari’s bohemian enclaves, with a plethora of exhibitions, film screenings and art workshops bringing a unique cultural flair to this underrated Italian port city.

An Image of Split, Croatia

Split

Split

Once overshadowed by nearby Dubrovnik, Split’s personality has made it a go-to for tourists in recent times. And with no shortage of things to see and do and delicious food to eat, it’s easy to see why.

A wander through Split’s Old Town offers up plenty of sights, chief among them being Diocletian’s Palace, a UNESCO-listed highlight that offers up arched gateways, marbled columns and the chance to scale the bell tower of the Cathedral of St Domnius, where incredible views of city and coast await.

Elsewhere, the year-round sun warms the palm-lined Riva, a seafront promenade where locals take their coffee very seriously. Grab a cup before heading to Bačvice Beach’s warming waters for some rest and relaxation.

For culture lovers, Meštrović Gallery and the Gallery of Fine Art are sure to satisfy, but be sure to leave room for Split’s food scene too – especially if fish is your thing.

An Image of Split, Croatia

Split

Once overshadowed by nearby Dubrovnik, Split’s personality has made it a go-to for tourists in recent times. And with no shortage of things to see and do and delicious food to eat, it’s easy to see why.

A wander through Split’s Old Town offers up plenty of sights, chief among them being Diocletian’s Palace, a UNESCO-listed highlight that offers up arched gateways, marbled columns and the chance to scale the bell tower of the Cathedral of St Domnius, where incredible views of city and coast await.

Elsewhere, the year-round sun warms the palm-lined Riva, a seafront promenade where locals take their coffee very seriously. Grab a cup before heading to Bačvice Beach’s warming waters for some rest and relaxation.

For culture lovers, Meštrović Gallery and the Gallery of Fine Art are sure to satisfy, but be sure to leave room for Split’s food scene too – especially if fish is your thing.

A View of Chairs near the shore in Mykonos, Greece

Mykonos

Mykonos

It may be Greece’s answer to Ibiza, but there’s more to Mykonos than its pulsating party scene. And though the main town, Hora, certainly gets busy, there’s still plenty of quiet spots to check out amongst its bevy of boutiques, cafes, and restaurants. Take the town’s windmills for instance. A short hike up the small hill away from the main town, it’s well worth making the trip here – especially at sunset.

At Hora’s Edge, meanwhile, the Rarity Gallery boasts frequently changing exhibitions featuring the best in contemporary painting, photography, and design. Elsewhere, to the south of Hora, the Aegean Maritime Museum, quiet and peaceful, lets visitors dive into Greece’s storied seafaring heritage, with an array of nautical artifacts from different centuries.

Delos is another highlight. The mythic birthplace of Apollo and Artemis, this uninhabited island plays host to several temple ruins and treasures. And when you’re done, the nearby beaches let the intrepid take up everything from windsurfing and kayaking to stand-up paddleboarding. With so much to see and do in Mykonos by day, it may be hard to muster up the energy to take in its fabled nightlife.

A View of Chairs near the shore in Mykonos, Greece

Mykonos

It may be Greece’s answer to Ibiza, but there’s more to Mykonos than its pulsating party scene. And though the main town, Hora, certainly gets busy, there’s still plenty of quiet spots to check out amongst its bevy of boutiques, cafes, and restaurants. Take the town’s windmills for instance. A short hike up the small hill away from the main town, it’s well worth making the trip here – especially at sunset.

At Hora’s Edge, meanwhile, the Rarity Gallery boasts frequently changing exhibitions featuring the best in contemporary painting, photography, and design. Elsewhere, to the south of Hora, the Aegean Maritime Museum, quiet and peaceful, lets visitors dive into Greece’s storied seafaring heritage, with an array of nautical artifacts from different centuries.

Delos is another highlight. The mythic birthplace of Apollo and Artemis, this uninhabited island plays host to several temple ruins and treasures. And when you’re done, the nearby beaches let the intrepid take up everything from windsurfing and kayaking to stand-up paddleboarding. With so much to see and do in Mykonos by day, it may be hard to muster up the energy to take in its fabled nightlife.

All Eastern Mediterranean Ports

Amazing East Mediterranean Cruise Deals

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

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Superb telephone conversation with Nickie. A lovely bloke that even laughed at my terrible humour whilst also finding me a cruise almost £100 cheaper than other operators. No long 'hold' queues or automated responses etc. Just a good proper human being helping arrange EVERYTHING in...

Mr Paul Cummings-22 September 2026

Booking was a piece of cake!

Rang up to query a few items and got a very nice lady who was extremely helpful and guided me through the process and I made a booking for end November. Very happy and a reasonable price as well.

Mr CAMPBELL WINDER-21 September 2026

Cruise Nation never fail to deliver a great deal.

Kerry was magnificent, very patient and super positive about finding me a deal that met my requirements. Took a couple of hours over two days but she delivered. Very happy with her commitment, especially on a Sunday morning

Mr Ian Shaw-21 September 2026

Booking with Cruise Nation

Cruise Nation staff well informed, and ensures that the client receives information about the choices they have made

Mr John Hindmarch-17 September 2026