A Woman standing on a cliff overlooking Mykonos, Greece

Destinations

East Mediterranean Cruises

Discover

"From the azure waters of the Aegean Sea to the sun-dappled shores of Cyprus, every destination tells a story of cultures intertwined through centuries"

Culture, Sun, Serenity

Are you ready to set sail on an unforgettable voyage to the breathtaking East Mediterranean? Imagine gliding through crystal-clear waters while surrounded by storied landscapes, ancient ruins, and the tantalizing taste of Mediterranean cuisine! With Cruise Nation, your dream holiday is just a wave away!

Dubrovnik - Croatia
An Image of the Walls of Dubrovnik in Croatia

From the sun-kissed shores of Greece to the vibrant markets of Turkey, the East Mediterranean is where history and modern life collide in dazzling harmony. Picture yourself wandering through the iconic streets of Santorini, where blue domes kiss the azure sky, or diving into the rich cultures of Istanbul, where every alleyway beckons you with the aroma of spices and freshly baked goods. Trust us, your taste buds are in for a treat!

Santorini - Greece
A view of the blue topped buildings of Santorini

Star Buy

The Iconic white buildings of Santorini

Our exceptional cruise packages provide you with the best value for a truly class-leading holiday experience. Explore the captivating ruins of Pompeii, bask in the beauty of the Amalfi Coast, or journey through the shimmering waters of the Aegean Sea—all while enjoying luxurious amenities on your cruise ship. Why settle for less when you can indulge in world-class dining and enthralling entertainment aboard?

A landscape view of Rhodes
Venice Square

What's the weather like in the Eastern Mediterranean?

There are plenty of great times to cruise the Eastern Mediterranean. But when it comes to weather, certain months are better than others, so before you book it’s good to know the prime times to cruise the region.

Do it your way

Having the freedom to cruise your way is just one of the many reasons why Cruise Nation is the way to go for the ultimate Eastern Mediterranean cruise getaway. We like to keep your options open here. If flying isn’t your thing, then our no-fly cruises do away with baggage restrictions and long queues.

Bari - Italy
The Cliffs of Bari, Italy

Our fly cruises, meanwhile, let you lengthen your leisure time either side of your holiday. Want to soak up the Athenian sun for a few days before you set sail? You can do that. Or maybe you’re not quite ready to leave Rhodes just yet? Simply add a few extra days onto your itinerary.

Istanbul - Turkey
A Landscape shot of Istanbul

Eastern Mediterranean Highlights

All Eastern Mediterranean Ports

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Amazing East Mediterranean Cruise Deals

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

Average Customer Rating:
4.9/5|
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Independent Service Rating based on 579 verified reviews.Read all reviews

Award

Super experience

Very knowledgeable, no upselling, more than happy to provide alternative dates/flights Very helpful

Mrs Karen Hunter Roberts-11 August 2025

Excellent service

Excellent service give them a ring it’s much easier, saved ourselves £275 from our usual cruise provider, tried a few nobody beat there price and a discount on Southampton port parking , what’s not to like .

Mr Keith McCarthy-10 August 2025

Excellent service

The lady who helped me book my holiday was patient, helpful and took the time to make sure I had what I wanted.

Mrs Karen Williams-09 August 2025

For us two 9/10 for all of us 9/10

Very good to us both and checking all. Lisa did a good job for us and we told friends and they booked onto same cruise and the total going and booked with cruise nation is ten .

Mr Stephen Symonds-09 August 2025