A Woman standing on a cliff overlooking Mykonos, Greece

Destinations

East Mediterranean Cruises

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"From the azure waters of the Aegean Sea to the sun-dappled shores of Cyprus, every destination tells a story of cultures intertwined through centuries"

Culture, Sun, Serenity

Are you ready to set sail on an unforgettable voyage to the breathtaking East Mediterranean? Imagine gliding through crystal-clear waters while surrounded by storied landscapes, ancient ruins, and the tantalizing taste of Mediterranean cuisine! With Cruise Nation, your dream holiday is just a wave away!

Dubrovnik - Croatia
An Image of the Walls of Dubrovnik in Croatia

From the sun-kissed shores of Greece to the vibrant markets of Turkey, the East Mediterranean is where history and modern life collide in dazzling harmony. Picture yourself wandering through the iconic streets of Santorini, where blue domes kiss the azure sky, or diving into the rich cultures of Istanbul, where every alleyway beckons you with the aroma of spices and freshly baked goods. Trust us, your taste buds are in for a treat!

Santorini - Greece
A view of the blue topped buildings of Santorini

Star Buy

The Iconic white buildings of Santorini

Our exceptional cruise packages provide you with the best value for a truly class-leading holiday experience. Explore the captivating ruins of Pompeii, bask in the beauty of the Amalfi Coast, or journey through the shimmering waters of the Aegean Sea—all while enjoying luxurious amenities on your cruise ship. Why settle for less when you can indulge in world-class dining and enthralling entertainment aboard?

A landscape view of Rhodes
Venice Square

What's the weather like in the Eastern Mediterranean?

There are plenty of great times to cruise the Eastern Mediterranean. But when it comes to weather, certain months are better than others, so before you book it’s good to know the prime times to cruise the region.

Do it your way

Having the freedom to cruise your way is just one of the many reasons why Cruise Nation is the way to go for the ultimate Eastern Mediterranean cruise getaway. We like to keep your options open here. If flying isn’t your thing, then our no-fly cruises do away with baggage restrictions and long queues.

Bari - Italy
The Cliffs of Bari, Italy

Our fly cruises, meanwhile, let you lengthen your leisure time either side of your holiday. Want to soak up the Athenian sun for a few days before you set sail? You can do that. Or maybe you’re not quite ready to leave Rhodes just yet? Simply add a few extra days onto your itinerary.

Istanbul - Turkey
A Landscape shot of Istanbul

Eastern Mediterranean Highlights

All Eastern Mediterranean Ports

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Amazing East Mediterranean Cruise Deals

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

Average Customer Rating:
4.9/5|
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Independent Service Rating based on 607 verified reviews.Read all reviews

Award

Booking a Virgin cruise.

Zoe provided an excellent service. She was very knowledgeable and had a very pleasant manner, and guided us to the holiday we wanted

Mr David Harris-25 August 2025

Middle east cruise, on norwegian sky

From start to finish Kayleigh was superb, she talked us through the process explaining everything we needed to know, she is very proficient at her job, not only did help myself and my husband, but also helped our australian friends, who were also very impressed...

-22 August 2025

Marvelous service

Kaylie was so helpful and efficient as well as being pleasant.

-21 August 2025

Great deal and knew the details of what to book

Friendly informative and an expert in cruise Bookings. Mary knew all the answers. Booked at a price discounted to Virgin Voyages direct..and Mary even managed to sort an upgraded cabin and some free on board spend. Perfect. Highly recommended.

Mr P.B-21 August 2025