A View of Iguassu Falls in Brazil

South America

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Peaks, passion and ports – South America in full colour

Our exclusive South America Cruise & Tour holidays pair the continent’s most iconic sights with the romance of the open sea. Stand in awe at the lost city of Machu Picchu, feel the thunder of Iguassu Falls, and stroll colonial streets where history hums through every cobblestone.

Machu Picchu - Peru
A landscape of Machu Picchu

Then swap the Andes for azure waters as your luxury cruise carries you to vibrant coastal cities and sun-soaked islands. From tango in Buenos Aires to samba in Rio, and from jungle trails to glittering bays, every itinerary is a rhythm-packed blend of culture, nature and ocean horizons.

Rio De Janiero - Brazil
A view of Rio De Janeiro from behind the Christ The Redeemer Statue

Star Buy

South America – the adventure of a lifetime, by land and by sea.

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

Average Customer Rating:4.9/5|
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Independent Service Rating based on 12,162 verified reviews.Read all reviews

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Trustworthy company

Have used cruise nation many times and feel each time we get excellent value and service

Mr David Allen-08 November 2026

Cruise Nation

As a first time cruiser I was unsure about the process. Lisa was amazing and talked me through it and what we like to do. Lisa sent me a few choices to pick from and tailored our fore coming cruise to us. We can’t wait...

Mrs Sandra Mundy-07 November 2026

Just review of booking so far

Knowlegable staff efficient booking service but just booked so can only base on that so far

Mr Graeme Foster-07 November 2026

Good customer service

Very good customer care services with customer

Mr Chak Hong Chan-06 November 2026