A View of Iguassu Falls in Brazil

South America

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Peaks, passion and ports – South America in full colour

Our exclusive South America Cruise & Tour holidays pair the continent’s most iconic sights with the romance of the open sea. Stand in awe at the lost city of Machu Picchu, feel the thunder of Iguassu Falls, and stroll colonial streets where history hums through every cobblestone.

Machu Picchu - Peru
A landscape of Machu Picchu

Then swap the Andes for azure waters as your luxury cruise carries you to vibrant coastal cities and sun-soaked islands. From tango in Buenos Aires to samba in Rio, and from jungle trails to glittering bays, every itinerary is a rhythm-packed blend of culture, nature and ocean horizons.

Rio De Janiero - Brazil
A view of Rio De Janeiro from behind the Christ The Redeemer Statue

Star Buy

South America – the adventure of a lifetime, by land and by sea.

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

Average Customer Rating:
4.9/5|
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Independent Service Rating based on 11,504 verified reviews.Read all reviews

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HOLIDAY 2026

VERY IMPRESSED WITH THE SERVICE, KNOWLEDGEABLE STAFF AND HAPPY WITH THEIR HELP. HAVE USED THEM MANY TIMES.

Mr Michael Franklin-14 December 2025

Booked with Confidence.

Excellent service and advice from Andrea. We are very happy we have booked our cruise for 2027. Andrea took time to explain everything in a happy and reassuring way. Thank you Cruisenation.

Mr Keith Holderness-11 December 2025

Easy to book

Excellent service from Scott. Real easy booking. Definitely recommend.

Mr Michael Noble-07 December 2025

Our Caribbean Cruise sold by Kit Glover

Kit Glover was our Travel Agent at Cruise National. We booked a Caribbean cruise on the Coral Prince ship for October 2026 for 16 nights. We are a group of 5 adults, so a lot of questions asked, so you could imagine trying to make...

Mrs Irene Beavis-04 December 2025