A View of Iguassu Falls in Brazil

South America

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Peaks, passion and ports – South America in full colour

Our exclusive South America Cruise & Tour holidays pair the continent’s most iconic sights with the romance of the open sea. Stand in awe at the lost city of Machu Picchu, feel the thunder of Iguassu Falls, and stroll colonial streets where history hums through every cobblestone.

Machu Picchu - Peru
A landscape of Machu Picchu

Then swap the Andes for azure waters as your luxury cruise carries you to vibrant coastal cities and sun-soaked islands. From tango in Buenos Aires to samba in Rio, and from jungle trails to glittering bays, every itinerary is a rhythm-packed blend of culture, nature and ocean horizons.

Rio De Janiero - Brazil
A view of Rio De Janeiro from behind the Christ The Redeemer Statue

Star Buy

South America – the adventure of a lifetime, by land and by sea.

* Price information

Prices on display are from and per person based on 2 sharing the lowest cabin grade unless otherwise stated. Gratuities are not included in any of these offers unless otherwise stated. Baggage charge may apply. No Booking fee is payable when you book online. Cruise Nation and Cruise Line Terms & Conditions apply. E&OE.

For the latest and most up to date availability & pricing, please click on a deal or call our team on 0333 455 8500

Average Customer Rating:
4.9/5|
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Independent Service Rating based on 11,914 verified reviews.Read all reviews

Award

Quality service at affordable prices

The lady we dealt with had a lot of patience and looked after us well.

Mr Daryl Berman-16 July 2026

Impressed and would recommend

Shirley was excellent and very knowledgeable. Good price when compared to other cruise agents.

Mrs Diane Kemp-15 July 2026

Great customer service and fabulous price

It was excellent customer service from Scott he produced a price on a few cruise options and as usual a really good price

Mr Andrew Devlin-14 July 2026

Excellent cruise company

Always a pleasure to book via Cruisenation. As I need an accessible cabin due to using a wheelchair I always phone up and the staff are always great. The new pay monthly is a definite plus for us too

Mrs Emma Pithers-12 July 2026