South America Cruise Ports: The Places That Make This Journey So Special

Some holidays are about switching off. Others are about seeing somewhere completely different. A cruise around South America manages to do both, and that’s a pretty tempting combination.
Think colourful cities, incredible coastlines, lively markets, spectacular scenery and food that deserves far more than a quick photograph. One day you could be exploring the streets of Buenos Aires, the next taking in the sights of Rio de Janeiro or watching the dramatic landscapes of the Chilean coastline pass by.
It’s a continent full of contrasts, and exploring it by ship gives you the chance to experience several destinations without constantly packing, unpacking and working out where you’re going next.
If South America has been sitting on your travel wish list, here’s a closer look at some of the destinations that make this part of the world such an exciting cruise adventure.
Rio de Janeiro: A City That Knows How to Make an Entrance

If there’s one city that knows how to grab your attention, it’s Rio de Janeiro.
With its famous beaches, dramatic mountain scenery and unmistakable atmosphere, Rio is a destination that feels larger than life. Copacabana and Ipanema offer those iconic stretches of sand, while the city’s restaurants, music and neighbourhoods give you plenty to explore away from the beach.
Then there’s Christ the Redeemer, standing high above the city on Corcovado Mountain. The views across Rio Bay and the surrounding landscape are the sort that make you stop, take a photograph and immediately wonder how you’re going to fit it all into one day.
I’d be tempted to spend time exploring the city before heading back to the ship. A beach afternoon, a little sightseeing and some Brazilian food sounds like a rather good way to spend a port day.
Buenos Aires: Tango, Culture and a Very Good Steak
Buenos Aires has a personality all of its own.
Argentina’s capital is famous for its tango heritage, elegant architecture, lively neighbourhoods and outstanding food. It’s a city where European influences meet Latin American energy, creating an atmosphere that’s difficult to replicate anywhere else.
San Telmo is particularly appealing, with its traditional streets, antique shops and lively markets. La Boca is another highlight, known for its brightly coloured buildings and artistic character.
And then there’s the food. Argentina is famous for its beef, and a traditional steakhouse experience would be high on my list. Add a glass of Malbec and you’ve got a pretty convincing reason to stay for dinner.
If you enjoy destinations with plenty of character, Buenos Aires is one of the South America cruise ports worth looking forward to.
Cartagena: Colourful Streets and Caribbean Charm
Cartagena brings a different flavour to a South American cruise adventure.
Located on Colombia’s Caribbean coast, this historic city is known for its colourful colonial buildings, flower-covered balconies, cobbled streets and impressive old city walls.
The historic centre is a wonderful place to explore on foot. You can wander through narrow streets, browse independent shops, stop for a coffee or find a restaurant serving traditional Colombian dishes.
The city’s history is just as fascinating as its appearance. Cartagena was once an important Spanish colonial port, and its fortifications and historic buildings tell the story of its past.
It’s also a great destination for anyone who enjoys taking photographs. Bright colours, beautiful architecture and tropical surroundings make it difficult to put the camera away.
Chile: Dramatic Coastlines and Incredible Landscapes

Chile is a country of extraordinary geographical contrasts. Stretching along the western edge of South America, it offers everything from desert landscapes in the north to forests, mountains and glaciers further south.
For cruise passengers, the Chilean coastline can provide some particularly memorable scenery.
Depending on the itinerary, you could encounter ports such as Valparaíso, a colourful coastal city famous for its hillside neighbourhoods, street art and historic funicular railways.
Further south, the scenery becomes increasingly dramatic. Patagonia is known for its rugged mountains, glaciers, fjords and vast open landscapes. Sailing through these waters can be a highlight in its own right, even before stepping ashore.
It’s one of the reasons I’d put a South American sailing high on the list for anyone who enjoys scenery as much as city breaks.
Montevideo: Uruguay’s Relaxed Capital
Montevideo might not always receive the same attention as Rio or Buenos Aires, but that’s part of its appeal.
Uruguay’s capital sits on the banks of the River Plate and has a relaxed atmosphere, attractive waterfront areas and a fascinating mix of historic and modern architecture.
The Ciudad Vieja, or Old Town, is a good place to start exploring. Its historic streets, cafés, markets and cultural attractions offer a glimpse into everyday life in Uruguay.
The Rambla, a long waterfront promenade, is another highlight. It’s ideal for a stroll, particularly when the sun starts to dip towards the horizon.
For food lovers, Uruguay is another destination where grilled meat and traditional dishes deserve attention. And if you’re keen to try something local, look out for mate, the country’s much-loved herbal drink.
Peru and Machu Picchu: An Adventure Beyond the Port

No South American travel guide would feel complete without mentioning Machu Picchu.
This extraordinary Inca citadel sits high in the Andes and is one of the continent’s most famous landmarks. Its mountain setting, remarkable stonework and fascinating history make it an unforgettable sight.
However, it’s worth understanding that Machu Picchu isn’t a cruise port. Visiting it generally requires additional travel inland, often involving a flight or an organised land-based itinerary.
For anyone wanting to combine a cruise with a more extensive South American adventure, a cruise-and-tour holiday could be worth considering. It allows you to explore further inland rather than limiting your trip to destinations reached directly by ship.
You can also explore Cruise Nation’s South America cruise and tour holidays if you’d like to combine time at sea with some of the continent’s famous landmarks.
Why Explore South America by Cruise?

South America is enormous, and travelling between its major destinations independently can involve a fair amount of planning.
A cruise offers a different way to experience the continent. You unpack once, settle into your cabin and let the ship take you between destinations.
There are several advantages:
- Multiple destinations: Experience different cities, cultures and landscapes within one holiday.
- Time to relax: Enjoy the restaurants, entertainment and facilities on board between port visits.
- Less travel planning: Your accommodation moves with you, so there’s no need to organise a new hotel every time you change destination.
- A different view: Some of South America’s most impressive scenery is best appreciated from the water.
- Something for different travellers: Whether you enjoy history, food, wildlife, beaches or city exploring, there’s plenty to discover.
Of course, no two itineraries are identical. Ports, sailing routes and the time spent in each destination depend on the particular cruise you choose.
What Can You Expect on an MSC South America Cruise?
MSC Cruises offers seasonal sailings in South America, giving passengers the opportunity to discover destinations across this fascinating region.
One of the attractions is the combination of time ashore and time on board. You can spend the day discovering a new city before returning to enjoy dinner, entertainment and a comfortable cabin.
It’s worth looking at the individual itinerary carefully before booking. Some sailings focus on particular stretches of coastline, while others include a different selection of ports. Departure ports, sailing dates and available excursions will also vary.
If you’re considering travelling with MSC, take a look at our MSC cruise deals to explore more of the ships and holidays available.
For a closer look at the South American options, visit our dedicated MSC Sizzling South America cruise deals page.
When Is the Best Time to Cruise South America?
South America covers a huge geographical area, so there isn’t one perfect month for every destination.
An important point to remember is that the seasons are reversed compared with the UK. When we’re wrapping up warm for winter, much of South America is heading into its summer months.
The southern hemisphere’s summer generally runs from December to February, while autumn runs from March to May. Winter falls between June and August, with spring from September to November.
For many South American cruise itineraries, the main sailing season runs through the southern hemisphere’s warmer months. However, the best time depends on the route, ports and experiences you’re hoping to enjoy.
If Patagonia and southern Chile are high on your wish list, weather conditions can be particularly important. If you’re more interested in cities such as Rio and Buenos Aires, you may have a wider range of seasonal options.
Always check the specific sailing dates and itinerary before making your decision.
Is a South America Cruise Worth It?
I’d say South America is one of those destinations that offers something genuinely different from the usual cruise holiday.
It’s not just about visiting another beach or ticking off another city. It’s about experiencing different cultures, trying new food, discovering fascinating history and seeing landscapes that can change dramatically from one destination to the next.
The South America cruise ports covered here each offer something different, whether that’s the energy of Rio, the character of Buenos Aires, the history of Cartagena or the dramatic scenery of Chile.
And that’s what makes the region so appealing. You aren’t simply booking a cruise; you’re opening the door to a much bigger adventure.
Ready to Discover South America?
If you’re tempted by colourful cities, spectacular scenery and a cruise that takes you somewhere a little different, South America deserves a place on your holiday list.
Explore our MSC Sizzling South America cruise deals and discover the available sailings, destinations and holiday options.
Your next adventure could be a lot further away than the Mediterranean. And that might be exactly what you need.
More like this

10 Best Party Holiday Destinations
Looking for the ultimate party getaway? Whether you’re looking for a boogie wonderland, a beach club retreat or someone who just loves soaking up the nightlife of a new city, we’ve got you covered with this comprehensive guide on party holiday destinations. From iconic destinations like Ibiza to more unique party destinations like Bali and…

The World’s Most Cultured Tourism Cities
Want to know which cities made our shortlist of the world’s foremost cultural melting pots? Join us as we rank renowned destinations like Paris, Rome, New York and Tokyo, all of which stake their claim as the world’s greatest places for sightseeing.

5 Shore Excursions on a Panama Canal Cruise
We recently named the Panama Canal as our cruise destination of the month thanks to its fascinating voyage through the isthmus connecting North and South America as well as the rich and varied culture that a Panama Canal cruise encompasses. Travelling from America’s Floridian east coast, through the Caribbean and Central America before landing on…